User:Mr. Ibrahem/Lincomycin

Mr. Ibrahem/Lincomycin
Clinical data
Trade names	Lincocin, Biocine, others
AHFS/Drugs.com	Monograph
MedlinePlus	a609005
Routes of; administration	IM/IV
Drug class	Lincosamide
Legal status
Legal status	US: ℞-only;
Pharmacokinetic data
Bioavailability	N/A
Elimination half-life	5.4 ± 1.0 h after IM or IV administration
Excretion	renal and biliary
Identifiers
	IUPAC name (2S,4R)-N-[(1R,2R)-2-Hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(methylsulfanyl)oxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;
Chemical and physical data
Formula	C18H34N2O6S
Molar mass	406.54 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(N[C@@H]([C@H]1O[C@H](SC)[C@H](O)[C@@H](O)[C@H]1O)[C@H](O)C)[C@H]2N(C)C[C@H](CCC)C2;
	InChI InChI=1S/C18H34N2O6S/c1-5-6-10-7-11(20(3)8-10)17(25)19-12(9(2)21)16-14(23)13(22)15(24)18(26-16)27-4/h9-16,18,21-24H,5-8H2,1-4H3,(H,19,25)/t9-,10-,11+,12-,13+,14-,15-,16-,18-/m1/s1 ; Key:OJMMVQQUTAEWLP-KIDUDLJLSA-N ;
	(what is this?) (verify)

Lincomycin, sold under the brand name Lincocin among others, is an antibiotic used to treat staphylococci and streptococci infections.^[1] Use is only recommended when other options are not suitable.^[1] It is used by injection into a muscle or vein.^[1]

Common side effects include nausea, diarrhea, rash, itchiness, muscle pains, ringing in the ears, and world spinning.^[1] Other side effects may include allergic reactions, Clostridioides difficile infection, low blood cells, and liver problems.^[1] Safety in pregnancy is unclear.^[1] It is a lincosamide, which is similar to but less effective than clindamycin.^[1]

Lincomycin was approved for medical use in the United States in 1964.^[1] In the United States 10 doses of 600 mg costs about 280 USD as of 2021.^[2] It is made from Streptomyces lincolnensis.^[1]

References[edit]

^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l "Lincomycin Monograph for Professionals". Drugs.com. Archived from the original on 27 January 2021. Retrieved 23 November 2021.
^ "Lincomycin Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 16 January 2021. Retrieved 23 November 2021.

[AHFS2021-1] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j ^k ^l "Lincomycin Monograph for Professionals". Drugs.com. Archived from the original on 27 January 2021. Retrieved 23 November 2021.

[2] "Lincomycin Prices, Coupons & Patient Assistance Programs". Drugs.com. Archived from the original on 16 January 2021. Retrieved 23 November 2021.

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