User:Mr. Ibrahem/Iron supplement
 Iron supplement from the late 19th and early 20th century | |
| Clinical data | |
|---|---|
| Trade names | Feosol, Feostat, Feratab, others |
| Other names | Iron pills, iron salts, ferrous salts, ferric salts |
| AHFS/Drugs.com | Monograph |
| Routes of administration | By mouth, by injection |
| Legal status | |
| Legal status |
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Iron supplements, also known as iron salts and iron pills, are a number of iron formulations used to treat and prevent iron deficiency including iron deficiency anemia.[5][6] For prevention they are only recommended in those with poor absorption, heavy menstrual periods, pregnancy, hemodialysis, or a diet low in iron.[6][7] Prevention may also be used in low birth weight babies.[6] They are taken by mouth, injection into a vein, or injection into a muscle.[6] While benefits may be seen in days up to two months may be required until iron levels return to normal.[2]
Common side effects include constipation, abdominal pain, dark stools, and diarrhea.[2] Other side effects, which may occur with excessive use, include iron overload and iron toxicity.[5][7] Ferrous salts used as supplements by mouth include ferrous fumarate, ferrous gluconate, ferrous succinate, and ferrous sulfate.[7] Injectable forms include iron dextran and iron sucrose.[7] They work by providing the iron needed for making red blood cells.[2]
Iron pills have been used medically since at least 1681, with an easy-to-use formulation being created in 1832.[8] It is on the World Health Organization's List of Essential Medicines.[9] Ferrous salts are available as a generic medication and over the counter.[5] The wholesale cost in the developing world is about US$0.05–0.63 per month.[10] In the United States a typical month of treatment costs less than $25.[5] Slow release formulations, while available, are not recommended.[6] In 2017, ferrous sulfate was the 92nd most commonly prescribed medication in the United States, with more than eight million prescriptions.[11][12]
References[edit]
- ^ "FERROUS salts - Essential drugs". medicalguidelines.msf.org. Archived from the original on 28 August 2021. Retrieved 30 August 2020.
- ^ a b c d "Iron Preparations, Oral". The American Society of Health-System Pharmacists. Archived from the original on 22 May 2016. Retrieved 8 January 2017.
- ^ "Single Drug Information – International Medical Products Price Guide". mshpriceguide. Archived from the original on 28 August 2021. Retrieved 17 August 2020.
- ^ "WHOCC - ATC/DDD Index". www.whocc.no. Archived from the original on 6 April 2017. Retrieved 30 August 2020.
- ^ a b c d Hamilton, Richart (2015). Tarascon Pocket Pharmacopoeia 2015 Deluxe Lab-Coat Edition. Jones & Bartlett Learning. p. 217. ISBN 9781284057560.
- ^ a b c d e British national formulary : BNF 69 (69 ed.). British Medical Association. 2015. pp. 660–664. ISBN 9780857111562.
- ^ a b c d World Health Organization (2009). Stuart MC, Kouimtzi M, Hill SR (eds.). WHO Model Formulary 2008. World Health Organization. pp. 247–250. hdl:10665/44053. ISBN 9789241547659.
- ^ Upfal, Jonathan (2006). Australian Drug Guide. Black Inc. pp. 378–379. ISBN 9781863951746. Archived from the original on 2017-09-18.
- ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
- ^ "Ferrous Salt". International Drug Price Indicator Guide. Archived from the original on 22 January 2018. Retrieved 8 December 2016.
- ^ "The Top 300 of 2020". ClinCalc. Archived from the original on 12 February 2021. Retrieved 11 April 2020.
- ^ "Ferrous Sulfate - Drug Usage Statistics". ClinCalc. Archived from the original on 8 July 2020. Retrieved 11 April 2020.