Talk:Marine pharmacognosy

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Molecular Biology: MCB

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I[edit]

I'm going to be working on this article for a bit. Let me know if you have some suggestions for the page. Sion55 (talk) 01:31, 3 July 2011 (UTC)[reply]

Introduction (insert picture of suba diving collection of samples)

Marine Pharmacognosy Marine organisms as sources

why marine organisms

evolutionary reasoning/adaptation of compound production

True producer

source is debated

similar compounds from different sources

e.gbryostatin, manazamine A, pseudoterisins

Biological diversity

animal phyla diversity

autotroph diversity

diversity of species

Diversity in general of areas

Examples of different organisms

tunicates, corals, sponges, etc...

Sample collection

near shore

corers

scuba

aquarious

submersibles

NP Isolation

extraction, purification, identification, assay

suitable solvent

target druglike compounds

biossay guided

mix and match the assay step

other possibilities

Structure elucidation

NMR, LC-MS, IR, etc...

Assays

MTT, LDH release, many others

e.g anticancer, antidiabetic, antiviral, antibacterial, antifungal, antiMS, etc...

Successful drugs

examples of drugs in trials

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