Talk:Costamere

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Merge[edit]

I don't see why there is a need for both a costamere article and a dystrophin-associated protein complex article. They seem to be the same thing. Currently, the costamere article uses both names interchangeably. The only difference I can imagine is if the "core" dystrophin-glycoprotein complex (DGC) is differentiated from the entire DGC network, which is then called the costamere. Cmcnicoll (talk) 01:23, 11 November 2009 (UTC)[reply]

I'd support a merge, but only if it was into this article - costamere is such a common term, much moreso than DAPC, that I think it would be best to have this page remain. Mokele (talk) 14:20, 11 November 2009 (UTC)[reply]

The DGC is a subset of the adhesion molecule complexes associated with costameres. ie: the terms are not interchangeable. Costameres also contain integrins and integrin-associated signaling molecules, and cadherins. Costamere really refers to the EM-visible, electron-dense structure, where DGC, integrin complex, and cadherin are (some of) the molecular components. — Preceding unsigned comment added by 24.30.100.218 (talk) 00:34, 28 August 2011 (UTC)[reply]