Sinecatechins

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A botanical drawing showing a plant with green leaves and white flowers
Sinecatechins is an extract from the leaves of Camellia sinensis.

Sinecatechins (USAN, trade names Veregen and Polyphenon E) is a specific water extract of green tea leaves from Camellia sinensis that is the active ingredient in an ointment approved by the FDA in 2006 as a botanical drug to treat genital warts.[1][2][3] Sinecatechins are mostly catechins, 55% of which is epigallocatechin gallate.[4] It was the first botanical drug approved by the US FDA.[2]

References[edit]

  1. ^ "Veregen label information" (PDF). Retrieved 2015-05-02.
  2. ^ a b Masters KP (2009). "New Drug Reviews: Sinecatechins (Veregen) for External Genital and Perianal Warts". Am Fam Physician. 80 (12): 1447–1454.
  3. ^ Fürst R, Zündorf I (2014). "Plant-derived anti-inflammatory compounds: hopes and disappointments regarding the translation of preclinical knowledge into clinical progress". Mediators Inflamm. 2014: 146832. doi:10.1155/2014/146832. PMC 4060065. PMID 24987194.
  4. ^ Mayeaux EJ, Dunton C (July 2008). "Modern management of external genital warts". J Low Genit Tract Dis. 12 (3): 185–192. doi:10.1097/LGT.0b013e31815dd4b4. PMID 18596459. S2CID 33302840.
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