5α-Dihydroaldosterone
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Names | |
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IUPAC name
11β,21-Dihydroxy-3,20-dioxo-5α-pregnan-18-al
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Preferred IUPAC name
(1S,3aS,3bS,5aS,9aS,9bS,10S,11aR)-10-Hydroxy-1-(hydroxyacetyl)-9a-methyl-7-oxohexadecahydro-11aH-cyclopenta[a]phenanthrene-11a-carbaldehyde | |
Identifiers | |
3D model (JSmol)
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ChemSpider | |
PubChem CID
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UNII | |
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Properties | |
C21H30O5 | |
Molar mass | 362.466 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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5α-Dihydroaldosterone is a metabolite of aldosterone that is formed by 5α-reductase.[1] It is a potent antinatriuretic agent similarly to but somewhat different from aldosterone.[1] It is produced in the kidneys.[1]
References[edit]
- ^ a b c Azzouni F, Godoy A, Li Y, Mohler J (2012). "The 5 alpha-reductase isozyme family: a review of basic biology and their role in human diseases". Adv Urol. 2012: 530121. doi:10.1155/2012/530121. PMC 3253436. PMID 22235201.