User:Mr. Ibrahem/Miglitol

Mr. Ibrahem/Miglitol
Clinical data
Trade names	Glyset
AHFS/Drugs.com	Monograph
MedlinePlus	a601079
License data	US FDA: Miglitol;
Pregnancy; category	AU: B3; ;
Routes of; administration	By mouth (tablets)
Drug class	α-glucosidase inhibitor
Legal status
Legal status	US: ℞-only;
Pharmacokinetic data
Bioavailability	Dose-dependent
Protein binding	Negligible (<4.0%)
Metabolism	Nil
Elimination half-life	2 hours
Excretion	Kidney (95%)
Identifiers
	IUPAC name (2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl); piperidine-3,4,5-triol;
Chemical and physical data
Formula	C8H17NO5
Molar mass	207.226 g·mol−1
3D model (JSmol)	Interactive image;
Density	1.458 g/cm3
Melting point	114 °C (237 °F)
	SMILES OCCN1[C@@H]([C@@H](O)[C@H](O)[C@@H](O)C1)CO;
	InChI InChI=1S/C8H17NO5/c10-2-1-9-3-6(12)8(14)7(13)5(9)4-11/h5-8,10-14H,1-4H2/t5-,6+,7-,8-/m1/s1 ; Key:IBAQFPQHRJAVAV-ULAWRXDQSA-N ;
	(verify)

Miglitol, sold under the brand name Glycet, is a medication used to treat type 2 diabetes.^[1] It is taken by mouth.^[1] It is used together with diet and exercise.^[1]

Common side effects include diarrhea, abdominal pain, and increased intestinal gas.^[1] Well there is no evidence of harm in pregnancy, such use has not been well studied.^[2] It is an α-glucosidase inhibitor which decreases the break down complex carbohydrates into glucose.^[1]

Miglitol was approved for medical use in the United States in 1996.^[1] It is available as a generic medication.^[3] In the United States it costs about 24 USD per month as of 2021.^[3]

References[edit]

^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j "Miglitol Monograph for Professionals". Drugs.com. Archived from the original on 14 August 2020. Retrieved 18 November 2021.
^ "Miglitol (Glyset) Use During Pregnancy". Drugs.com. Archived from the original on 3 December 2020. Retrieved 18 November 2021.
^ ^a ^b "Miglitol Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 18 November 2021.

[AHFS2021-1] ^ ^a ^b ^c ^d ^e ^f ^g ^h ⁱ ^j "Miglitol Monograph for Professionals". Drugs.com. Archived from the original on 14 August 2020. Retrieved 18 November 2021.

[2] "Miglitol (Glyset) Use During Pregnancy". Drugs.com. Archived from the original on 3 December 2020. Retrieved 18 November 2021.

[GX2021-3] "Miglitol Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 18 November 2021.

[1]

[2]

[3]