User:Mr. Ibrahem/Crotamiton

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Mr. Ibrahem/Crotamiton
Clinical data
AHFS/Drugs.comMonograph
Identifiers
  • (E)-N-Ethyl-N-(2-methylphenyl)but-2-enamide
Chemical and physical data
FormulaC13H17NO
Molar mass203.285 g·mol−1
3D model (JSmol)
  • O=C(N(c1ccccc1C)CC)/C=C/C
  • InChI=1S/C13H17NO/c1-4-8-13(15)14(5-2)12-10-7-6-9-11(12)3/h4,6-10H,5H2,1-3H3/b8-4+ checkY
  • Key:DNTGGZPQPQTDQF-XBXARRHUSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Crotamiton, sold under the brand name Eurax among others, is a used to treat scabies, lice, and itching.[1] For scabies it appear to work less well compared to permethrin.[1] It is applied to the skin.[2]

Common side effects include rash and allergic reactions.[1] Safety in pregnancy is unclear.[2] Its mechanism of action is unknown.[1]

Crotamiton has been approved in the United States for medical use since at least 1949.[1] In the United Kingdom 100 grams of cream costs the NHS about £4.[2] In the United States 60 grams costs about 500 USD.[3]

References[edit]

  1. ^ a b c d e f g "Crotamiton Monograph for Professionals". Drugs.com. Archived from the original on 30 June 2019. Retrieved 7 January 2022.
  2. ^ a b c BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 1309. ISBN 978-0857114105.
  3. ^ "Crotamiton Prices, Coupons & Savings Tips - GoodRx". GoodRx. Retrieved 7 January 2022.