User:Mr. Ibrahem/Carmustine

From Wikipedia, the free encyclopedia
Mr. Ibrahem/Carmustine
Clinical data
Trade namesBiCNU, Gliadel, others
AHFS/Drugs.comMonograph
MedlinePlusa682060
License data
Drug classAntineoplastic agents
 ☒NcheckY (what is this?)  (verify)

Carmustine, sold under the brand name BiCNU among others, is a medication used for cancer.[1] Specifically it is used for brain tumors, multiple myeloma, lymphoma, and melanoma.[1] It may be used as palliative chemotherapy.[2] It is generally used by injection into a vein or as part of an implant in the brain.[1]

Common side effects include nausea, kidney problems, lung inflammation, and bone marrow suppression.[2] Other side effects may include secondary cancers, hair loss, and allergic reactions.[2][3] Use in pregnancy may harm the baby.[2] It is a nitrosourea compound and alkylating agent.[1]

Carmustine was approved for medical use in the United States in 1977.[1] In the United States it costs about 2,800 USD per 100 mg dose as of 2023.[4] In the United Kingdom implants cost the NHS about 650 £ each as of 2021.[3]

References[edit]

  1. ^ a b c d e f "Carmustine Monograph for Professionals". Drugs.com. Archived from the original on 17 August 2022. Retrieved 3 December 2023.
  2. ^ a b c d e "DailyMed - CARMUSTINE- carmustine kit". dailymed.nlm.nih.gov. Archived from the original on 4 December 2023. Retrieved 3 December 2023.
  3. ^ a b BNF 81: March-September 2021. BMJ Group and the Pharmaceutical Press. 2021. p. 937. ISBN 978-0857114105.
  4. ^ "BiCNU Prices, Coupons, Copay & Patient Assistance". Drugs.com. Archived from the original on 9 June 2023. Retrieved 3 December 2023.