Urologic chronic pelvic pain syndrome

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Urologic chronic pelvic pain syndrome (UCPPS) is ongoing bladder pain in either sex, chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) in men and interstitial cystitis[1][2][3] or painful bladder syndrome (IC/PBS) in women.[4][5]

It was coined as an umbrella term for use in research into urologic pain syndromes in men and women.

Treatment[edit]

Multimodal therapy is the most successful treatment option in chronic pelvic pain,[6] and includes physical therapy,[7] myofascial trigger point release,[7] relaxation techniques,[7] α-blockers,[8] and phytotherapy.[9][10] The UPOINT diagnostic approach suggests that antibiotics are not recommended unless there is clear evidence of infection.[11]

Research[edit]

In 2007, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), part of the United States National Institutes of Health (NIH), began using UCPPS as a term to refer to chronic pelvic pain syndromes (interstitial cystitis|interstitial cystitis/bladder pain syndrome (IC/BPS) in women and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) in men).[12]

MAPP Research Network[edit]

The NIDDK established the Multidisciplinary Approach to the Study of Chronic Pelvic Pain (MAPP) Research Network in 2008.[13]

MAPP Network scientists use a whole–body, systemic approach to the study of UCPPS, as well as investigating potential relationships between UCPPS and other chronic conditions that are sometimes seen in IC/PBS and CP/CPPS patients, such as irritable bowel syndrome, fibromyalgia, and chronic fatigue syndrome.[13]

References[edit]

  1. ^ Dimitrakov J, Joffe HV, Soldin SJ, Bolus R, Buffington CA, Nickel JC (February 2008). "Adrenocortical hormone abnormalities in men with chronic prostatitis/chronic pelvic pain syndrome". Urology. 71 (2): 261–6. doi:10.1016/j.urology.2007.09.025. PMC 2390769. PMID 18308097.
  2. ^ Masiutin MG, Yadav MK (2022). "Letter to the editor regarding the article "Adrenocortical hormone abnormalities in men with chronic prostatitis/chronic pelvic pain syndrome"". Urology. 169: 273. doi:10.1016/j.urology.2022.07.051. ISSN 0090-4295. PMID 35987379. S2CID 251657694.
  3. ^ Dimitrakoff J, Nickel JC (2022). "AUTHOR REPLY". Urology. 169: 273–274. doi:10.1016/j.urology.2022.07.049. ISSN 0090-4295. PMID 35985522. S2CID 251658492.
  4. ^ Dimitrakov J, Dimitrakova E (2009). "Urologic chronic pelvic pain syndrome--looking back and looking forward". Folia Med (Plovdiv). 51 (3): 42–4. PMID 19957562.
  5. ^ Adamian L, Urits I, Orhurhu V, Hoyt D, Driessen R, Freeman JA, Kaye AD, Kaye RJ, Garcia AJ, Cornett EM, Viswanath O (May 2020). "A Comprehensive Review of the Diagnosis, Treatment, and Management of Urologic Chronic Pelvic Pain Syndrome". Curr Pain Headache Rep. 24 (6): 27. doi:10.1007/s11916-020-00857-9. PMID 32378039. S2CID 218513050.
  6. ^ Potts JM (2005). "Therapeutic options for chronic prostatitis/chronic pelvic pain syndrome". Current Urology Reports. 6 (4): 313–7. doi:10.1007/s11934-005-0030-5. PMID 15978236. S2CID 195364765.
  7. ^ a b c Potts J, Payne RE (May 2007). "Prostatitis: Infection, neuromuscular disorder, or pain syndrome? Proper patient classification is key". Cleve Clin J Med. 74 (Suppl 3): S63–71. doi:10.3949/ccjm.74.suppl_3.s63. PMID 17549825.
  8. ^ Yang G, Wei Q, Li H, Yang Y, Zhang S, Dong Q (2006). "The effect of alpha-adrenergic antagonists in chronic prostatitis/chronic pelvic pain syndrome: a meta-analysis of randomized controlled trials". J. Androl. 27 (6): 847–52. doi:10.2164/jandrol.106.000661. PMID 16870951. ...treatment duration should be long enough (more than 3 months)
  9. ^ Shoskes DA, Zeitlin SI, Shahed A, Rajfer J (1999). "Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial". Urology. 54 (6): 960–3. doi:10.1016/S0090-4295(99)00358-1. PMID 10604689.
  10. ^ Elist J (2006). "Effects of pollen extract preparation Prostat/Poltit on lower urinary tract symptoms in patients with chronic nonbacterial prostatitis/chronic pelvic pain syndrome: a randomized, double-blind, placebo-controlled study". Urology. 67 (1): 60–3. doi:10.1016/j.urology.2005.07.035. PMID 16413333.
  11. ^ Sandhu J, Tu HY (2017). "Recent advances in managing chronic prostatitis/chronic pelvic pain syndrome". F1000Res. 6: 1747. doi:10.12688/f1000research.10558.1. PMC 5615772. PMID 29034074.
  12. ^ Clemens JQ, Mullins C, Kusek JW, Kirkali Z, Mayer EA, Rodríguez LV, et al. (August 2014). "The MAPP research network: a novel study of urologic chronic pelvic pain syndromes". BMC Urol. 14: 57. doi:10.1186/1471-2490-14-57. PMC 4134515. PMID 25085007.
  13. ^ a b "A New Look at Urological Chronic Pelvic Pain". Multi-Disciplinary Approach to the Study of Chronic Pelvic Pain. Retrieved 8 March 2021.
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