Talk:Protease

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Description[edit]

Can someone add "protease segments protenes"? The description is a little klunky. There is no mention of how this word is pronounced. Is it "pro-teez" or "pro-tee-aze"? —Preceding unsigned comment added by 99.135.66.222 (talk) 16:18, 19 June 2010 (UTC)[reply]

"ase" means "breaker of." So it is protee-ase. Rumiton (talk) 14:08, 19 September 2010 (UTC)[reply]

Tool use[edit]

Can someone add some information what are proteases actually used for commercially? there are thousands of tons produced each year... Maximilianh

—Preceding unsigned comment added by 157.136.241.109 (talk) 10:08, 6 November 2008 (UTC)[reply]

Protease is redirected here. Shouldn't it be the other way around? I used to do PhD studies on proteases... and the word "peptidase" exists in the name of a few proteases, but I think it is pretty oldfashioned. Protease was the word we used. / Habj 17:24, 11 August 2005 (UTC)[reply]

Endopeptidase? JFW | T@lk 18:42, 11 August 2005 (UTC)Where is it found?? in the pancreas and the stomach.[reply]

Not all proteases are endopeptidases. Endopeptidases are proteases that cleaves a protein chain in the middle of the sequence, while exoproteases "chews" from the end of the chain. /Habj 00:35, 15 August 2005 (UTC)[reply]

doesn't 'peptidases' refer primarily to the activity of proteases in the stomach? There is an inactive pro-peptidase that is turned into the active peptidase by acid (HCL) in the stomach. I think peptidases don't only inactivate proteins, like a protease does, but splits proteins without specificity into aminoacids --Picobyte 19:19, 21 March 2006 (UTC)[reply]

maybe this link is usefull? Extracellular proteases and their inhibitors ingenetic diseases of the central nervous system [1]

Possible image[edit]

User:TimVickers produced the following image which I nominated for deletion last week because it wasn't being used anywhere. User:Deryck Chan was nice enough to look through my nominations at my request and thought that this one was worth saving, and might be useful on this article. ~ Bigr Tex 16:55, 5 February 2007 (UTC)[reply]

Used this image elsewhere. —The preceding unsigned comment was added by Twooars (talk • contribs) 03:57, 15 April 2007 (UTC).[reply]

Peptidases[edit]

There could easily be a whole artical devoted to peptidases, rather than have it just redirected to this page. In a magazine I see an ad for a foot-care product has has protease as an ingredient; would "protease (subtilisin)" be effective for removing calluses? http://www.xenna.com/product_callex.html

Minor 2013 overhaul[edit]

I've made some changes that hopefully have improved the article:

Finally cleared up orphan references from 2009!
- I've integrated most into the text where it's obvious
- The article is still a little sparse on references though
Added leader image (though not necessarily the most appropriate)
Added comparison of mechanisms and image (pretty proud of that one)
Moved degradation section into mechanism and functions header
Added evolutionary classification (MEROPS)
Separated occurrence in to sections by kingdom
Linked to main articles in inhibitors and uses
Generally expanded a few sections
Added see also links
Do we need a history section?

Hopeully these justify increasing the article's quality class from Start to C. What do you think? T. Shafee (Evo&Evo) (talk) 02:54, 9 December 2013 (UTC)[reply]

fungi?[edit]

"Proteases can be found in animals, plants, bacteria, archea and viruses." Asmrulz (talk) 20:47, 1 May 2014 (UTC)[reply]

Assessment comment[edit]

The comment(s) below were originally left at Talk:Protease/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

This article is not accessible to a layman, and uses sentence forms which are confusing even for someone with the requisite background material. Instead of using run-on sentences with multiple commas and brackets, a better approach might even be using sentence fragments or point lists.

Last edited at 00:30, 11 June 2007 (UTC). Substituted at 03:28, 30 April 2016 (UTC)

Pronunciation[edit]

Could someone who knows how the IPA template works please add the pronunciation to the intro paragraph? Thanks. Psu256 (talk) 15:16, 18 September 2019 (UTC)[reply]

Circular defintion?[edit]

The Trypsin Wikipedia page starts "Trypsin (EC 3.4.21.4) is a serine protease..." and this Protease Wikipedia page begins "A protease (also called a peptidase or proteinase) is a Trypsin..."

I am not experienced enough in this field yet to know how to address this edit, but maybe one of you out there can help make this non-circular between the two pages! Cheers.