Talk:Persin

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Chemical structure[edit]

Persin was identified as (Z,Z)-1-(acetyloxy)-2-hydroxy-12,15-heneicosadien-4-one in 1995. A rough condensed structure is as follows: CH3C=OOCH2CHOHCH2C=OR, where R has two unconjugated double bonds (both double bonds are Z, or "trans"). Note also that the hydroxyl and the ketonyl carbonyl have an aldol relation (a beta-hydroxy ketone), typically created by an aldol condensation.

CAS[edit]

The CAS-link gives "No CAS Registry Number® matched your search."

91.156.5.58 (talk) 19:26, 1 December 2014 (UTC)[reply]

The link goes to a Chemical Abstracts page that only verifies "common chemicals", and everything else gives the result you saw. -- Ed (Edgar181) 14:25, 2 December 2014 (UTC)[reply]

Other Foods Toxic to Pets[edit]

Regarding the section of other foods toxic to pets, shouldn't this go in its own page? It has nothing to do with persin. Just my $0.02.
Naisenu 19:57, 31 August 2007 (UTC)[reply]

Yeah, that's all covered elsewhere. I removed it. --Joelmills 02:44, 1 September 2007 (UTC)[reply]

The references need to be tracked back to the original source. Given the wild birds and my chickens love the avocados on my trees, when I found out they were considered highly poisonous to birds, I went looking for references. Eventually tracked it back, to the only study I could find. They injected(!) avocado directly into budgie (I think) birds. A number of them died. Hardly conclusive evidence that avocados are poisonous to birds. I have tracked down references, but don't have access to the journal, and it appears to not be online. These are the three ref's that need checking out:

https://www.ncbi.nlm.nih.gov/pubmed/2914792 https://www.ncbi.nlm.nih.gov/pubmed/1577644 https://www.ncbi.nlm.nih.gov/pubmed/1639676

Why are humans different?[edit]

Does anyone know why humans don't react like other mammals? How about chimps? If there are any references to reliable sources explaining why, this would be a nice addition to the page. Guy Macon (talk) 17:07, 15 September 2011 (UTC)[reply]

harmful for humans[edit]

The research paper analyszing the effect on mammary cells and heart cells speaks even about "mammals", i'm not sure how it can be concluded it is safe for humans? 100mg/kg are given for serious necrosis in mice mammary gland tissue (and also the myocardial tissue). Shaddim (talk) 16:10, 20 October 2016 (UTC) there seems to be an paper between 1997 and 2006 which concluded that Persin is harmless/not very harmfull to human mammary gland cells...but couldn't track it down. would be great if someone could add it. Shaddim (talk) 13:30, 21 October 2016 (UTC)[reply]