SCPEP1

SCPEP1
Identifiers
Aliases	SCPEP1, HSCP1, RISC, serine carboxypeptidase 1
External IDs	MGI: 1921867 HomoloGene: 41443 GeneCards: SCPEP1
Gene location (Human) Chr. Chromosome 17 (human) Band 17q22 Start 56,978,129 bp End 57,006,768 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 C Start 88,814,846 bp End 88,846,291 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte left lobe of thyroid gland right lobe of thyroid gland gallbladder ascending aorta right coronary artery gastric mucosa minor salivary glands right lung skin of abdomen Top expressed in calvaria pineal gland external carotid artery internal carotid artery iris skin of abdomen carotid body intercostal muscle vas deferens cervix More reference expression data BioGPS More reference expression data
Gene ontology Molecular function carboxypeptidase activity peptidase activity hydrolase activity serine-type carboxypeptidase activity Cellular component extracellular region cytosol extracellular exosome Biological process proteolysis involved in cellular protein catabolic process retinoic acid metabolic process negative regulation of blood pressure proteolysis Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 59342 74617 Ensembl ENSG00000121064 ENSMUSG00000000278 UniProt Q9HB40 Q920A5 RefSeq (mRNA) NM_021626 NM_029023 RefSeq (protein) NP_067639 NP_083299 Location (UCSC) Chr 17: 56.98 – 57.01 Mb Chr 11: 88.81 – 88.85 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Retinoid-inducible serine carboxypeptidase is an enzyme that in humans is encoded by the SCPEP1 gene.

Further reading

• Robb GB, Rana TM (May 2007). "RNA helicase A interacts with RISC in human cells and functions in RISC loading". Molecular Cell. 26 (4): 523–537. doi:10.1016/j.molcel.2007.04.016. PMID 17531811.
• Zhang Z, Henzel WJ (October 2004). "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Science. 13 (10): 2819–2824. doi:10.1110/ps.04682504. PMC 2286551. PMID 15340161.
• Zhang H, Li XJ, Martin DB, Aebersold R (June 2003). "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry". Nature Biotechnology. 21 (6): 660–666. doi:10.1038/nbt827. PMID 12754519. S2CID 581283.