Ribosome biogenesis protein BRX1 homolog

BRIX1
Identifiers
Aliases	BRIX1, BRIX, BXDC2, BRX1, biogenesis of ribosomes, biogenesis of ribosomes BRX1
External IDs	OMIM: 618466 MGI: 1915082 HomoloGene: 10133 GeneCards: BRIX1
Gene location (Human)
Chr.	Chromosome 5 (human)
End	34,925,996 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	10,486,033 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; ganglionic eminence; ; islet of Langerhans; ; rectum; ; left uterine tube; ; left coronary artery; ; canal of the cervix; ; tibial nerve; ; skin of abdomen; ; monocyte;
	Top expressed in
	secondary oocyte; ; morula; ; primitive streak; ; otic placode; ; hair follicle; ; abdominal wall; ; maxillary prominence; ; somite; ; Paneth cell; ; condyle;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	RNA binding; protein binding;
Cellular component	nucleolus; nucleus;
Biological process	ribosome biogenesis; ribosomal large subunit assembly;
	Sources:Amigo / QuickGO
Orthologs
	55299
	67832
	ENSG00000113460
	ENSMUSG00000022247
	Q8TDN6
	Q9DCA5
	NM_018321
	NM_026396
	NP_060791
	NP_080672
	Wikidata
View/Edit Human	View/Edit Mouse

Ribosome biogenesis protein BRX1 homolog (BRIX1) also known as brix domain-containing protein 2 (BXDC2) is a protein that in humans is encoded by the BRIX1 gene.^[5]^[6]

References[edit]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000113460 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000022247 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
^ "Entrez Gene: BXDC2 brix domain containing 2".

Further reading[edit]

Andersen JS, Lyon CE, Fox AH, Leung AK, Lam YW, Steen H, et al. (2002). "Directed proteomic analysis of the human nucleolus". Curr. Biol. 12 (1): 1–11. Bibcode:2002CBio...12....1A. doi:10.1016/S0960-9822(01)00650-9. PMID 11790298. S2CID 14132033.
Kaser A, Bogengruber E, Hallegger M, Doppler E, Lepperdinger G, Jantsch M, et al. (2002). "Brix from xenopus laevis and brx1p from yeast define a new family of proteins involved in the biogenesis of large ribosomal subunits". Biol. Chem. 382 (12): 1637–47. doi:10.1515/BC.2001.199. PMID 11843177. S2CID 23636837.
Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

This article on a gene on human chromosome 5 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000113460 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000022247 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12477932-5] Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, et al. (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

[entrez-6] "Entrez Gene: BXDC2 brix domain containing 2".

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