PRMT7
Protein arginine methyltransferase 7 is a protein that in humans is encoded by the PRMT7 gene.[1] Arginine methylation is an apparently irreversible protein modification catalyzed by arginine methyltransferases, such as PMT7, using S-adenosylmethionine (AdoMet) as the methyl donor. Arginine methylation is implicated in signal transduction, RNA transport, and RNA splicing.[1][2]
References[edit]
- ^ a b "Protein arginine methyltransferase 7". Retrieved 2011-12-06.
- ^ Miranda, T. B.; Miranda, M.; Frankel, A.; Clarke, S. (2004). "PRMT7 is a Member of the Protein Arginine Methyltransferase Family with a Distinct Substrate Specificity". Journal of Biological Chemistry. 279 (22): 22902–22907. doi:10.1074/jbc.M312904200. PMID 15044439.
Further reading[edit]
- Jelinic, P.; Stehle, J. C.; Shaw, P. (2006). "The Testis-Specific Factor CTCFL Cooperates with the Protein Methyltransferase PRMT7 in H19 Imprinting Control Region Methylation". PLOS Biology. 4 (11): e355. doi:10.1371/journal.pbio.0040355. PMC 1609128. PMID 17048991.
- Lee, J. -H.; Cook, J. R.; Yang, Z. H.; Mirochnitchenko, O.; Gunderson, S. I.; Felix, A. M.; Herth, N.; Hoffmann, R.; Pestka, S. (2004). "PRMT7, a New Protein Arginine Methyltransferase That Synthesizes Symmetric Dimethylarginine". Journal of Biological Chemistry. 280 (5): 3656–3664. doi:10.1074/jbc.M405295200. PMID 15494416.
- Gonsalvez, G. B.; Tian, L.; Ospina, J. K.; Boisvert, F. -M.; Lamond, A. I.; Matera, A. G. (2007). "Two distinct arginine methyltransferases are required for biogenesis of Sm-class ribonucleoproteins". The Journal of Cell Biology. 178 (5): 733–740. doi:10.1083/jcb.200702147. PMC 2064538. PMID 17709427.
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