Draft:Se-Jin Lee
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Se-Jin Lee | |
|---|---|
| Born | October 20, 1958 Seoul, South Korea |
| Alma mater | Harvard University |
| Known for | mechanisms of controlled muscle hypertrophy utilizing myostatin |
| Spouse | Emily Lucy Germain-Lee |
| Children | Benjamin Charles Germain Lee |
| Awards | Rolf Luft Award |
| Scientific career | |
| Fields | Cell biology Myostatin ActivinA Muscle hypertrophy |
| Institutions | American Academy of Arts & Sciences National Academy of Sciences National Academy of Inventors |
Se-Jin Lee (October 20, 1958 – ) is an American biologist and professor at the University of Connecticut and at the Jackson Laboratory.
His work has had wide impact in the understanding as to how skeletal muscle mass is controlled. He discovered several proteins in the large "TGFbeta" family of cytokines, including myostatin, also known as "GDF8", Activin A, GDF11, etc.
Most of his work has employed the use of genetically modified mice. For example, mice which were made to be null for myostatin/GDF8 demonstrated almost a two-fold increase in skeletal muscle mass, which showed that myostatin is a natural inhibitor of muscle differentiation and growth.