File:Combined small cell lung carcinoma with extensive mucosal involvement; possible SCLC in situ Case 271 (9255562385).jpg
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Summary
| Description |
This is a surgical lobectomy specimen of small cell lung carcinoma (SCLC) combined with large cell neuroendocrine carcinoma exhibiting extensive tumor involvement of bronchial epipthelium, glands and glandular ducts. Much of the mucosal involvement is not immediately adjacent to areas of invasive SCLC. Although it has been suggested (and it is possible) that mucosal tumor involvement in this case represents invasion by underlying invasive tumor, I believe that that explanation is unlikely. A precursor of SCLC has not yet been identified. Its identification and acceptance would require studies carefully focusing on the examination of the bronchial mucosa in a large number of resection and/or autopsy specimens. At the present time present specimens of this type are not often encountered in any one institution. In this photo the bronchial epithelium is extensively replaced by tumor cells. An area of invasive small cell carcinoma is seen in the left lower quadrant. Note that much of the involved bronchial epithelium is not adjacent to invasive carcinoma. |
| Date | |
| Source | Combined small cell lung carcinoma with extensive mucosal involvement; possible SCLC in situ Case 271 |
| Author | Yale Rosen from USA |
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This image was originally posted to Flickr by Pulmonary Pathology at https://flickr.com/photos/30950973@N03/9255562385 (archive). It was reviewed on 3 October 2019 by FlickreviewR 2 and was confirmed to be licensed under the terms of the cc-by-sa-2.0. |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 07:30, 3 October 2019 | | 1,280 × 960 (721 KB) | Netha Hussain | Transferred from Flickr via #flickr2commons |
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