File:RNAi-simplified.svg

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Description
English: Overview of RNA interference. The dicer enzymes produce siRNA from double-stranded RNA and mature miRNA from precursor miRNA. miRNA or siRNA is bound to an argonaute enzyme and an effector complex is formed, either a RISC (RNA-induced silencing complex) or RITS (RNA-induced transcriptional silencing) complex. RITS affects the rate of transcription by histone and DNA methylation, whereas RISC degrades mRNA to prevent it from being translated.
Date
Source This figure is adapted from one by Matzke MA, Matzke AJM (2004) Planting the Seeds of a New Paradigm. PLoS Biol 2(5): e133 doi:10.1371/journal.pbio.0020133.
Author
  • This figure is adapted from one by Matzke MA, Matzke AJM
  • Silvia3
  • vectorization: Own work
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current16:57, 3 February 2012Thumbnail for version as of 16:57, 3 February 2012835 × 625 (26 KB)Razorbliss{{Information |Description={{en|Overview of RNA interference. The dicer enzymes produce siRNA from double-stranded RNA and mature miRNA from precursor miRNA. miRNA or siRNA is bound to an argonaute enzyme and an effector complex is formed, either a RISC (
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