File:Lisch nodules.JPG
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Summary
| Description |
English: Lisch nodules are numerous nodules of dendritic melanocytes in aggregates within the iris. They are brown-yellow, round shape, raised papules as seen with slit lamp examination in the iris of patients with Neurofibromatosis type 1(>90% of cases) together with scattered café au lait pigmented skin lesions and multiple neurifibromas (superficial or deep) in skin or other organs. Similar nodules are also found in Watson syndrome which is in addition characterized by macrocephaly, pulmonary stenosis, short status and low intelligence. No treatment is required but a close follow-up of main diseases is mandatory for avoiding any serious complications. Ελληνικά: Τα οζίδια Lisch είναι πολυάριθμα μελαχρωματικά στίγματα στην ίριδα του ματιού άφθονα σε μελανοκύτταρα. Κλινικά, χαρακτηρίζονται σαν κίτρινες ή καφέ, υπερυψωμένες κηλίδες στην ίριδα ασθενών με Νευροινωμάτωση τύπου 1 (> 90% των περιπτώσεων) μαζί με κηλίδες (café au lait) και νευροινώματα (επιφανειακά ή εν τώ βάθει) στο δέρμα ή σε αλλά όργανα. Παρόμοια οζίδια έχουν βρεθεί μαζί με μακροκεφαλία, χαμηλό ύψος, πνευματική καθυστέρηση και πνευμονική στένωση στο σύνδρομο Watson. Τα οζίδια Lisch δεν επηρεάζουν την όραση και δεν απαιτούν θεραπεία παρά μόνο στενή παρακολούθηση για αποφυγή τυχών επιπλοκών από την κυρία νόσο. |
| Date | |
| Source | Own work |
| Author | Dimitrios Malamos |
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This image was uploaded as part of European Science Photo Competition 2015. |
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 13:10, 23 November 2015 | | 3,888 × 2,592 (3.78 MB) | Dmalamos | User created page with UploadWizard |
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