Summary

The Domain Organisation of EVH proteins (from amino terminus (left) to carboxy terminus (right)). 1) EVH1 domain - responsible for correct localisation EVH proteins - binds w:FP4 motifs. 2) PxxP motifs - bind w:SH2 domains] of SRC and ABL w:kinases - possibly responsible for regulation. 3) GP5 motifs - Bind the w:actin carrier protein w:Profilin 4) G-Actin binding site - Binds G-(w:monomeric)actin. 5) F-actin binding site - Binds F-(polymerised) actin. 6) Tetramerisation helix - allows EVH proteins to tetramerise - can be homo- & hetero- tetramers.

Licensing

I, the copyright holder of this work, hereby publish it under the following license:

	This file is licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license. Subject to disclaimers.
	You are free: to share – to copy, distribute and transmit the work to remix – to adapt the work Under the following conditions: attribution – You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. share alike – If you remix, transform, or build upon the material, you must distribute your contributions under the same or compatible license as the original.
	This licensing tag was added to this file as part of the GFDL licensing update.http://creativecommons.org/licenses/by-sa/3.0/CC BY-SA 3.0Creative Commons Attribution-Share Alike 3.0truetrue

Permission is granted to copy, distribute and/or modify this document under the terms of the GNU Free Documentation License, Version 1.2 or any later version published by the Free Software Foundation; with no Invariant Sections, no Front-Cover Texts, and no Back-Cover Texts. A copy of the license is included in the section entitled GNU Free Documentation License. Subject to disclaimers.http://www.gnu.org/copyleft/fdl.htmlGFDLGNU Free Documentation Licensetruetrue