File:8-oxoG forming Hoogsten base pair with dA.svg

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Summary

Description 8-Oxoguanine (8-oxoG, left), in syn conformation, forming a Hoogsteen base pair with deoxyadenosine triphosphate (dATP, right). Created using ACD/ChemSketch 10.0 and Inkscape.
Date
Source Vector version of Image:Oxog.jpg. Adapted from Wang Y, Schlick T (2007). "Distinct energetics and closing pathways for DNA polymerase beta with 8-oxoG template and different incoming nucleotides". BMC Struct Biol 7: 7. PMID 17313689. doi:10.1186/1472-6807-7-7 and Hsu GW, Ober M, Carell T, Beese LS (September 2004). "Error-prone replication of oxidatively damaged DNA by a high-fidelity DNA polymerase". Nature 431 (7005): 217–21. PMID 15322558. doi:10.1038/nature02908.
Author Fvasconcellos
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Public domain This image of a simple structural formula is ineligible for copyright and therefore in the public domain, because it consists entirely of information that is common property and contains no original authorship.

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20 August 2008

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current23:18, 20 August 2008Thumbnail for version as of 23:18, 20 August 2008783 × 421 (3 KB)Fvasconcellos{{validSVG}} {{Information |Description= {{w|8-Oxoguanine}} ('''8-oxoG''', left), in ''syn'' conformation, forming a {{w|Hoogsteen base pair}} with {{w|deoxyadenosine triphosphate}} ('''dATP''', right). Created using [http://www.acdlabs.com/download/chem
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